STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5K4F656Uncharacterized protein. (86 aa)    
Predicted Functional Partners:
A0A3Q0KNQ0
Putative trithorax protein ash2.
    
 0.735
Smp_053300
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.663
A0A5K4FAQ4
Uncharacterized protein.
      
 0.609
A0A3Q0KNK7
Putative retinoblastoma binding protein.
    
 0.603
A0A5K4EQJ9
Putative retinoblastoma binding protein.
    
 0.603
A0A3Q0KDM4
Golgi membrane protein sb140 (Yip1b), putative.
   
 
 0.564
A0A3Q0KUE3
Selenoprotein W, putative.
      
 0.524
A0A5K4F743
Uncharacterized protein.
    
 0.521
Smp_074610
Histone H3; Belongs to the histone H3 family.
    
 0.521
Smp_082240
Histone H3; Belongs to the histone H3 family.
    
 0.521
Your Current Organism:
Schistosoma mansoni
NCBI taxonomy Id: 6183
Other names: S. mansoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.