STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rad23Putative uv excision repair protein rad23. (354 aa)    
Predicted Functional Partners:
A0A3Q0KE68
Putative peptide n-glycanase (Pngase).
    
 0.998
PSMD4_SCHMA
26S proteasome non-ATPase regulatory subunit 4; Binds and presumably selects ubiquitin-conjugates for destruction; Belongs to the proteasome subunit S5A family.
   
 0.994
Smp_089430
Ubiquitin (Ribosomal protein L40), putative.
   
 0.988
A0A3Q0KD76
Putative dna repair protein xp-C / rad4.
   
 0.978
A0A5K4F3I4
Uncharacterized protein.
   
 0.978
SmPOH
Pad1 homolog.
   
 0.978
A0A3Q0KKA3
Putative 26s protease regulatory subunit; Belongs to the AAA ATPase family.
   
 0.971
Smp_012470
Putative 26s protease regulatory subunit; Belongs to the AAA ATPase family.
    
 0.967
A0A3Q0KVB9
ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]
   
 0.966
Smp_018240.3
Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.
   
 0.961
Your Current Organism:
Schistosoma mansoni
NCBI taxonomy Id: 6183
Other names: S. mansoni
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