Smp_050130 protein (Schistosoma mansoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Smp_050130

Uncharacterized protein. (326 aa)

Predicted Functional Partners:

A0A3Q0KVB9

0.993

A0A3Q0KKY7

0.985

A0A3Q0KH17

0.972

Rad23

0.945

Smp_019060

0.709

A0A3Q0KQK3

0.705

A0A5K4F7X2

0.705

A0A5K4F9B8

0.705

A0A5K4FAY4

0.705

Smp_170450

0.705

Your Current Organism:

Schistosoma mansoni

NCBI taxonomy Id: 6183
Other names: S. mansoni

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A3Q0KH17	A0A3Q0KKY7	A0A3Q0KH17	A0A3Q0KKY7	Putative heat shock protein 70 (Hsp70)-interacting protein.	Putative scythe/bat3.	0.758
A0A3Q0KH17	A0A3Q0KVB9	A0A3Q0KH17	A0A3Q0KVB9	Putative heat shock protein 70 (Hsp70)-interacting protein.	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	0.934
A0A3Q0KH17	Rad23	A0A3Q0KH17	A9CBJ4	Putative heat shock protein 70 (Hsp70)-interacting protein.	Putative uv excision repair protein rad23.	0.956
A0A3Q0KH17	Smp_019060	A0A3Q0KH17	G4VG47	Putative heat shock protein 70 (Hsp70)-interacting protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.902
A0A3Q0KH17	Smp_050130	A0A3Q0KH17	G4LWL3	Putative heat shock protein 70 (Hsp70)-interacting protein.	Uncharacterized protein.	0.972
A0A3Q0KKY7	A0A3Q0KH17	A0A3Q0KKY7	A0A3Q0KH17	Putative scythe/bat3.	Putative heat shock protein 70 (Hsp70)-interacting protein.	0.758
A0A3Q0KKY7	A0A3Q0KVB9	A0A3Q0KKY7	A0A3Q0KVB9	Putative scythe/bat3.	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	0.825
A0A3Q0KKY7	Rad23	A0A3Q0KKY7	A9CBJ4	Putative scythe/bat3.	Putative uv excision repair protein rad23.	0.492
A0A3Q0KKY7	Smp_050130	A0A3Q0KKY7	G4LWL3	Putative scythe/bat3.	Uncharacterized protein.	0.985
A0A3Q0KQK3	Rad23	A0A3Q0KQK3	A9CBJ4	PIP49_C domain-containing protein.	Putative uv excision repair protein rad23.	0.456
A0A3Q0KQK3	Smp_050130	A0A3Q0KQK3	G4LWL3	PIP49_C domain-containing protein.	Uncharacterized protein.	0.705
A0A3Q0KVB9	A0A3Q0KH17	A0A3Q0KVB9	A0A3Q0KH17	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	Putative heat shock protein 70 (Hsp70)-interacting protein.	0.934
A0A3Q0KVB9	A0A3Q0KKY7	A0A3Q0KVB9	A0A3Q0KKY7	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	Putative scythe/bat3.	0.825
A0A3Q0KVB9	Rad23	A0A3Q0KVB9	A9CBJ4	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	Putative uv excision repair protein rad23.	0.966
A0A3Q0KVB9	Smp_019060	A0A3Q0KVB9	G4VG47	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.739
A0A3Q0KVB9	Smp_050130	A0A3Q0KVB9	G4LWL3	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	Uncharacterized protein.	0.993
A0A5K4F7X2	Rad23	A0A5K4F7X2	A9CBJ4	Uncharacterized protein.	Putative uv excision repair protein rad23.	0.455
A0A5K4F7X2	Smp_050130	A0A5K4F7X2	G4LWL3	Uncharacterized protein.	Uncharacterized protein.	0.705
A0A5K4F9B8	Rad23	A0A5K4F9B8	A9CBJ4	Uncharacterized protein.	Putative uv excision repair protein rad23.	0.455
A0A5K4F9B8	Smp_050130	A0A5K4F9B8	G4LWL3	Uncharacterized protein.	Uncharacterized protein.	0.705