STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smp_076530Regulator of chromosome condensation, putative. (767 aa)    
Predicted Functional Partners:
Smp_079430.2
GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
 0.998
Smp_166310
Putative ran gtpase-activating protein.
   
 
 0.944
Smp_053300
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
  0.914
Smp_051210.1
Importin subunit alpha; Belongs to the importin alpha family.
   
 
 0.899
A0A5K4F0D4
Uncharacterized protein.
   
 
 0.895
Smp_168490
Importin alpha, putative.
   
 
 0.895
Smp_151190
Retinal rod rhodopsin-sensitive cgmp 3',5'-cyclic phosphodiesterase, putative.
    
 
 0.889
Smp_038080.1
Putative importin beta-1.
    
 
 0.885
A0A3Q0KCR0
Putative ran-binding protein.
   
 0.883
A0A5K4EA57
Putative ran-binding protein.
   
 0.883
Your Current Organism:
Schistosoma mansoni
NCBI taxonomy Id: 6183
Other names: S. mansoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.