STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MS3_04342Citrate synthase; Belongs to the citrate synthase family. (470 aa)    
Predicted Functional Partners:
MS3_01444
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.999
MS3_02136
Malate dehydrogenase.
  
 0.999
MS3_06938
ATP-citrate synthase.
  
 0.995
MS3_07730
Malate dehydrogenase, cytoplasmic; Belongs to the LDH/MDH superfamily.
  
 0.995
MS3_02353
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.994
MS3_07158
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.994
MS3_09457
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 0.992
MS3_04225
Aspartate aminotransferase.
   
 0.989
MS3_04599
Acetyl-coenzyme A synthetase.
  
 0.987
MS3_08048
2-oxoglutarate dehydrogenase-like, mitochondrial.
  
 0.986
Your Current Organism:
Schistosoma haematobium
NCBI taxonomy Id: 6185
Other names: S. haematobium
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.