STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTX1Deltex E3 ubiquitin ligase 1. (606 aa)    
Predicted Functional Partners:
NOTCH2
Notch receptor 2.
    
 0.944
NOTCH1
Notch receptor 1.
    
 0.918
ITCH
E3 ubiquitin-protein ligase.
    
 0.728
WWP1
E3 ubiquitin-protein ligase.
    
 0.701
WWP2
E3 ubiquitin-protein ligase.
    
 0.701
LOC100583249
E3 ubiquitin-protein ligase.
    
 0.701
DNER
Delta/notch like EGF repeat containing.
   
 0.695
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 
 0.632
ENSNLEP00000034619
Ubiquitin-like domain-containing protein.
    
 0.631
NRARP
NOTCH regulated ankyrin repeat protein.
    
 0.598
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.