MCOLN1 protein (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

MCOLN1

Mucolipin 1. (580 aa)

Predicted Functional Partners:

MCOLN2

0.974

MCOLN3

0.970

TFEB

0.700

TFE3

0.700

ATP6V1H

0.692

USH1C

0.601

LY6D

0.577

CTSA

0.523

TRPM1

0.512

TRPC1

0.511

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V1H	MCOLN1	ENSNLEP00000037474	ENSNLEP00000001025	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	Mucolipin 1.	0.692
ATP6V1H	MCOLN3	ENSNLEP00000037474	ENSNLEP00000035967	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	Mucolipin 3.	0.485
ATP6V1H	TFE3	ENSNLEP00000037474	ENSNLEP00000009717	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	Transcription factor binding to IGHM enhancer 3.	0.498
ATP6V1H	TFEB	ENSNLEP00000037474	ENSNLEP00000005964	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	Transcription factor EB.	0.644
CTSA	MCOLN1	ENSNLEP00000008289	ENSNLEP00000001025	Carboxypeptidase; Belongs to the peptidase S10 family.	Mucolipin 1.	0.523
CTSA	TFEB	ENSNLEP00000008289	ENSNLEP00000005964	Carboxypeptidase; Belongs to the peptidase S10 family.	Transcription factor EB.	0.511
LY6D	MCOLN1	ENSNLEP00000001596	ENSNLEP00000001025	Lymphocyte antigen 6 family member D.	Mucolipin 1.	0.577
MCOLN1	ATP6V1H	ENSNLEP00000001025	ENSNLEP00000037474	Mucolipin 1.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.692
MCOLN1	CTSA	ENSNLEP00000001025	ENSNLEP00000008289	Mucolipin 1.	Carboxypeptidase; Belongs to the peptidase S10 family.	0.523
MCOLN1	LY6D	ENSNLEP00000001025	ENSNLEP00000001596	Mucolipin 1.	Lymphocyte antigen 6 family member D.	0.577
MCOLN1	MCOLN2	ENSNLEP00000001025	ENSNLEP00000012181	Mucolipin 1.	Mucolipin 2.	0.974
MCOLN1	MCOLN3	ENSNLEP00000001025	ENSNLEP00000035967	Mucolipin 1.	Mucolipin 3.	0.970
MCOLN1	TFE3	ENSNLEP00000001025	ENSNLEP00000009717	Mucolipin 1.	Transcription factor binding to IGHM enhancer 3.	0.700
MCOLN1	TFEB	ENSNLEP00000001025	ENSNLEP00000005964	Mucolipin 1.	Transcription factor EB.	0.700
MCOLN1	TRPC1	ENSNLEP00000001025	ENSNLEP00000005912	Mucolipin 1.	Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family.	0.511
MCOLN1	TRPM1	ENSNLEP00000001025	ENSNLEP00000036900	Mucolipin 1.	Transient receptor potential cation channel subfamily M member 1.	0.512
MCOLN1	USH1C	ENSNLEP00000001025	ENSNLEP00000021528	Mucolipin 1.	USH1 protein network component harmonin.	0.601
MCOLN2	MCOLN1	ENSNLEP00000012181	ENSNLEP00000001025	Mucolipin 2.	Mucolipin 1.	0.974
MCOLN2	MCOLN3	ENSNLEP00000012181	ENSNLEP00000035967	Mucolipin 2.	Mucolipin 3.	0.979
MCOLN2	TFEB	ENSNLEP00000012181	ENSNLEP00000005964	Mucolipin 2.	Transcription factor EB.	0.428

page 1 of 3

Server load: low (14%) [HD]

Permalink

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About