Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PNMTPhenylethanolamine N-methyltransferase. (282 aa)    
Predicted Functional Partners:
DBH
Dopamine beta-hydroxylase.
   
 
 0.971
COMT
Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.
     
 0.940
MAOB
Amine oxidase.
     
 0.927
MAOA
Amine oxidase.
     
 0.927
PTH
Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.
      
 0.698
TH
Tyrosine hydroxylase.
      
 0.694
SP1
Sp1 transcription factor.
      
 0.692
MOXD1
Monooxygenase DBH like 1.
   
 
 0.585
PAH
Phenylalanine hydroxylase.
      
 0.546
AGMO
Alkylglycerol monooxygenase; Belongs to the sterol desaturase family.
      
 0.545
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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