Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
PLCL2Phosphoinositide phospholipase C. (1120 aa)    
Predicted Functional Partners:
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
   0.797
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
   0.775
CCDC186
Coiled-coil domain containing 186.
    
   0.575
DPH3
Diphthamide biosynthesis 3.
   
  
 0.489
HCRTR1
Hypocretin receptor 1; Belongs to the G-protein coupled receptor 1 family.
   
 0.488
HCRTR2
Hypocretin receptor 2; Belongs to the G-protein coupled receptor 1 family.
   
 0.488
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 
 0.482
OXNAD1
Oxidoreductase NAD binding domain containing 1.
      
 0.482
GALNT15
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.481
RNF17
Ring finger protein 17.
      
 0.481
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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