Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CHD9Chromodomain helicase DNA binding protein 9. (2607 aa)    
Predicted Functional Partners:
ENSNLEP00000029307
Uncharacterized protein.
 
      0.898
CHD8
Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...]
   
    0.808
CHD7
Chromodomain helicase DNA binding protein 7.
   
    0.805
CTNNB1
Catenin beta 1.
   
 0.720
RTF1
RTF1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.614
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.595
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 
 0.569
PHF3
PHD finger protein 3.
   
 0.560
ZFP90
ZFP90 zinc finger protein.
   
 0.555
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 
 0.555
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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