STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLKlotho. (855 aa)    
Predicted Functional Partners:
FGF23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
    
 0.999
FGFR1
Fibroblast growth factor receptor.
   
 0.999
ENSNLEP00000033446
Uncharacterized protein.
    
 0.955
FGF19
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.952
IRS1
Insulin receptor substrate 1.
     
 0.946
FGF21
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.944
IRS4
Insulin receptor substrate 4.
     
 0.939
IRS2
Insulin receptor substrate 2.
     
 0.939
FGFR4
Fibroblast growth factor receptor.
   
 0.917
FGF16
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.906
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.