Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CR2Complement C3d receptor 2. (1092 aa)    
Predicted Functional Partners:
CD19
CD19 molecule.
   
 0.974
C3
Complement C3.
   
 0.910
LOC100584814
C-type lectin domain-containing protein.
   
 0.893
CLEC1B
C-type lectin domain family 1 member B.
    
 0.809
LOC100596445
Uncharacterized protein.
   
 0.797
CHRNA4
Cholinergic receptor nicotinic alpha 4 subunit.
    
 
 0.788
CLDN18
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.786
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase 3.
     
 0.745
PLK1
Serine/threonine-protein kinase PLK.
    
 
 0.723
ITGA4
Integrin subunit alpha 4; Belongs to the integrin alpha chain family.
     
 0.710
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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