Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CLEC4MC-type lectin domain family 4 member M. (375 aa)    
Predicted Functional Partners:
LOC100591293
Uncharacterized protein.
    
 0.912
KSR1
Kinase suppressor of ras 1.
    
 0.907
RHOA
Ras homolog family member A.
    
 0.905
CD209
CD209 molecule.
  
  
 
0.901
PLK3
Polo like kinase 3.
    
  0.901
ARHGEF12
Rho guanine nucleotide exchange factor 12.
     
 0.900
ICAM3
Uncharacterized protein.
   
 0.809
ICAM2
Intercellular adhesion molecule 2.
     
 0.689
BTN2A1
Butyrophilin subfamily 2 member A1.
     
 0.626
FAM217B
Family with sequence similarity 217 member B.
    
   0.573
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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