Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACRAcrosin; Belongs to the peptidase S1 family. (439 aa)    
Predicted Functional Partners:
SPA17
Sperm surface protein Sp17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.
    
 
 0.822
ACRBP
Acrosin binding protein.
   
  
 0.821
ZPBP
Zona pellucida binding protein.
   
  
 0.717
TNP1
Transition protein 1.
   
  
 0.705
IZUMO1
Izumo sperm-egg fusion 1.
   
 
 0.704
AKAP3
A-kinase anchoring protein 3.
   
  
 0.697
IZUMO4
IZUMO family member 4.
   
 
 0.693
AKAP4
A-kinase anchoring protein 4.
   
  
 0.680
TESMIN
Testis expressed metallothionein like protein.
    
 
 0.659
CD9
Tetraspanin.
   
 
 0.614
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (12%) [HD]