STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CGASCyclic GMP-AMP synthase. (523 aa)    
Predicted Functional Partners:
IRF3
IRF tryptophan pentad repeat domain-containing protein.
      
 0.554
DDX41
DEAD-box helicase 41.
      
 0.530
TBK1
TANK binding kinase 1.
      
 0.494
MAVS
Uncharacterized protein.
      
 0.483
SAMHD1
Uncharacterized protein.
   
  
 0.471
THRSP
Thyroid hormone responsive.
    
  0.460
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 
 0.445
ICAM2
Intercellular adhesion molecule 2.
   
  
 0.422
TLR3
Toll like receptor 3; Belongs to the Toll-like receptor family.
      
 0.412
G1RD82_NOMLE
Uncharacterized protein.
    
 0.405
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (36%) [HD]