Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SBSPONSomatomedin B and thrombospondin type 1 domain containing. (264 aa)    
Predicted Functional Partners:
UNC5A
Unc-5 netrin receptor A.
    
 
 0.707
RSPO1
R-spondin 1.
      
 0.698
RSPO4
R-spondin 4.
      
 0.693
TRMT9B
tRNA methyltransferase 9B (putative).
      
 0.661
POFUT2
Uncharacterized protein.
     
 0.650
AASDH
Aminoadipate-semialdehyde dehydrogenase.
  
 
 0.648
SEMA5A
Semaphorin 5A.
     
 0.631
ZNF326
Zinc finger protein 326; Belongs to the AKAP95 family.
      
 0.607
MED14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 0.605
RAE1
Ribonucleic acid export 1.
    
 0.593
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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