Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ATRXATRX chromatin remodeler. (2485 aa)    
Predicted Functional Partners:
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
 0.975
MECP2
MBD domain-containing protein.
    
 0.867
PHIP
Pleckstrin homology domain interacting protein.
   
 0.865
RAD50
Zinc-hook domain-containing protein.
  
 
 0.859
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 
 0.853
SMC5
SMC_N domain-containing protein.
  
 0.851
H3-4
Histone H3; Belongs to the histone H3 family.
    
 0.850
THOC2
THO complex 2.
   
 
 0.837
BRD4
Bromodomain containing 4.
   
 
 0.833
SCAF11
SR-related CTD associated factor 11.
   
   0.828
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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