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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (326 aa)    
Predicted Functional Partners:
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 
 0.946
CCNA1
Cyclin A1; Belongs to the cyclin family.
   
 
 0.946
CCND1
Cyclin D1; Belongs to the cyclin family.
     
 0.930
PTBP1
Polypyrimidine tract binding protein 1.
   
 0.923
AGO2
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
   
 
 0.912
PRKAA2
Non-specific serine/threonine protein kinase.
     
 0.906
PRKAA1
Non-specific serine/threonine protein kinase.
     
 0.906
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2.
    
 0.900
PRKAB1
Protein kinase AMP-activated non-catalytic subunit beta 1.
    
 0.900
PRKAG3
Protein kinase AMP-activated non-catalytic subunit gamma 3.
     
  0.900
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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