Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (896 aa)    
Predicted Functional Partners:
BUB1B
BUB1 N-terminal domain-containing protein.
   
0.999
NDC80
NDC80 kinetochore complex component.
   
 0.999
BUB3
BUB3 mitotic checkpoint protein.
   
 0.999
MAD2L1
Mitotic arrest deficient 2 like 1.
   
 0.998
CENPF
Centromere protein F.
   
 0.997
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 0.997
CENPE
Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.997
PLK1
Serine/threonine-protein kinase PLK.
   
 0.995
ENSNLEP00000026532
Uncharacterized protein.
    
 0.995
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.995
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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