Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GSDMAGasdermin A. (433 aa)    
Predicted Functional Partners:
DSG4
Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  
 
 
 0.792
TGM5
Transglutaminase 5.
   
  
 0.701
LOC100600677
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
      
 0.551
BIRC7
Baculoviral IAP repeat containing 7.
      
 0.544
CASP1
Caspase 1; Belongs to the peptidase C14A family.
   
  
 0.537
KPRP
Keratinocyte proline rich protein.
   
 
 0.530
IL37
Interleukin-1.
      
 0.522
IL23A
Interleukin 23 subunit alpha.
  
     0.482
AIM2
Absent in melanoma 2.
    
 
 0.480
KRTDAP
Keratinocyte differentiation associated protein.
  
  
 0.474
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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