Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KSR1Kinase suppressor of ras 1. (831 aa)    
Predicted Functional Partners:
BRAP
BRCA1 associated protein.
    
 0.989
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
0.983
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
 0.962
MARK3
Non-specific serine/threonine protein kinase.
   
 0.954
KSR2
Kinase suppressor of ras 2.
     
 
0.930
CD209
CD209 molecule.
    
 0.908
CLEC4M
C-type lectin domain family 4 member M.
    
 0.907
MAP2K2
Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.
   
 0.881
LOC100591293
Uncharacterized protein.
    
 0.881
ENSNLEP00000042936
Protein kinase domain-containing protein.
   
 0.881
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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