| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AP2M1 | AP2S1 | ENSNLEP00000007470 | ENSNLEP00000025040 | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | 0.998 |
| AP2M1 | DHX29 | ENSNLEP00000007470 | ENSNLEP00000001737 | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. | 0.717 |
| AP2M1 | ITSN1 | ENSNLEP00000007470 | ENSNLEP00000048437 | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | Intersectin 1. | 0.978 |
| AP2M1 | ITSN2 | ENSNLEP00000007470 | ENSNLEP00000001028 | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | Intersectin 2. | 0.990 |
| AP2S1 | AP2M1 | ENSNLEP00000025040 | ENSNLEP00000007470 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | 0.998 |
| AP2S1 | DHX29 | ENSNLEP00000025040 | ENSNLEP00000001737 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. | 0.661 |
| AP2S1 | ITSN1 | ENSNLEP00000025040 | ENSNLEP00000048437 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | Intersectin 1. | 0.979 |
| AP2S1 | ITSN2 | ENSNLEP00000025040 | ENSNLEP00000001028 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | Intersectin 2. | 0.989 |
| DDX3X | DHX29 | ENSNLEP00000028150 | ENSNLEP00000001737 | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. | 0.714 |
| DDX3X | EIF3B | ENSNLEP00000028150 | ENSNLEP00000010568 | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. | Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. | 0.748 |
| DDX3X | EIF4G1 | ENSNLEP00000028150 | ENSNLEP00000035819 | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. | Eukaryotic translation initiation factor 4 gamma 1. | 0.848 |
| DDX3X | PDCD11 | ENSNLEP00000028150 | ENSNLEP00000024355 | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. | Programmed cell death 11. | 0.519 |
| DDX3X | UTP14A | ENSNLEP00000028150 | ENSNLEP00000018533 | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. | UTP14A small subunit processome component. | 0.509 |
| DHX29 | AP2M1 | ENSNLEP00000001737 | ENSNLEP00000007470 | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | 0.717 |
| DHX29 | AP2S1 | ENSNLEP00000001737 | ENSNLEP00000025040 | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | 0.661 |
| DHX29 | DDX3X | ENSNLEP00000001737 | ENSNLEP00000028150 | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. | 0.714 |
| DHX29 | EIF3B | ENSNLEP00000001737 | ENSNLEP00000010568 | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. | Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. | 0.682 |
| DHX29 | EIF4G1 | ENSNLEP00000001737 | ENSNLEP00000035819 | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. | Eukaryotic translation initiation factor 4 gamma 1. | 0.641 |
| DHX29 | ITSN1 | ENSNLEP00000001737 | ENSNLEP00000048437 | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. | Intersectin 1. | 0.759 |
| DHX29 | ITSN2 | ENSNLEP00000001737 | ENSNLEP00000001028 | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. | Intersectin 2. | 0.929 |
STRING v12.5 is now available!
