Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TGOLN2Trans-golgi network protein 2. (481 aa)    
Predicted Functional Partners:
AP2M1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.874
VAMP4
Vesicle associated membrane protein 4.
   
 0.850
AP2S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
  0.759
GALNT2
Polypeptide N-acetylgalactosaminyltransferase.
    
 0.754
IGF2R
Insulin like growth factor 2 receptor.
   
 0.722
GCC1
GRIP and coiled-coil domain containing 1.
     
 0.687
EDEM3
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
    
   0.653
AP1B1
AP complex subunit beta.
    
  0.642
AP2B1
AP complex subunit beta.
    
  0.642
ENSNLEP00000030293
Uncharacterized protein.
    
  0.642
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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