Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RUFY1RUN and FYVE domain containing 1. (674 aa)    
Predicted Functional Partners:
RUFY2
RUN and FYVE domain containing 2.
  
 
0.976
RAB4A
RAB4A, member RAS oncogene family.
    
 0.973
TGFB1I1
Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
   
    0.945
BMX
Tyrosine-protein kinase.
    
 0.884
RAB14
RAB14, member RAS oncogene family.
    
 0.791
ENSNLEP00000045506
RUN domain-containing protein.
    
 
 0.771
RUFY3
RUN and FYVE domain containing 3.
    
 
 0.748
LOC101175949
Uncharacterized protein.
    
 0.741
UTP25
UTP25 small subunit processor component.
    
 
 0.728
BTK
Tyrosine-protein kinase.
    
 0.691
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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