Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL27Interleukin 27. (241 aa)    
Predicted Functional Partners:
IL27RA
Interleukin 27 receptor subunit alpha.
    
 0.998
JAK1
Tyrosine-protein kinase.
    
 0.957
JAK2
Tyrosine-protein kinase.
    
 0.955
TYK2
Tyrosine-protein kinase.
    
 0.948
IL6ST
Interleukin 6 signal transducer.
    
  0.935
EBI3
Epstein-Barr virus induced 3.
    
  0.826
IL6R
Interleukin 6 receptor.
    
 0.767
CNTFR
Ciliary neurotrophic factor receptor.
    
 0.746
STAT3
Signal transducer and activator of transcription.
    
 0.687
STAT1
Signal transducer and activator of transcription.
    
 0.678
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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