STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WWP1E3 ubiquitin-protein ligase. (922 aa)    
Predicted Functional Partners:
ITCH
E3 ubiquitin-protein ligase.
  
 
0.984
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.933
NEDD4
NEDD4 E3 ubiquitin protein ligase.
    
0.930
RNF41
Ring finger protein 41.
    
 0.923
SMURF2
E3 ubiquitin-protein ligase.
     
0.921
CBL
Cbl proto-oncogene.
    
 0.919
UBE2L5
Ubiquitin conjugating enzyme E2 L5; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.869
HIVEP3
Human immunodeficiency virus type I enhancer binding protein 3.
    
 0.843
SMAD7
Mothers against decapentaplegic homolog.
    
 0.827
SPART
Spartin.
    
 
 0.824
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.