STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK2Non-specific serine/threonine protein kinase. (524 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.999
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.993
PAK1
Non-specific serine/threonine protein kinase.
  
 
0.990
RAC2
Rac family small GTPase 2.
   
 0.977
CASP3
Caspase 3; Belongs to the peptidase C14A family.
    
 0.970
NCK2
Cytoplasmic protein.
    
 0.969
NCK1
Cytoplasmic protein.
    
 0.968
ARHGAP10
Rho GTPase activating protein 10.
   
 0.965
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.965
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
0.957
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.