Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CASC3CASC3 exon junction complex subunit. (702 aa)    
Predicted Functional Partners:
EIF4A3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
    
 0.998
RBM8A
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
   
 0.991
UPF2
UPF2 regulator of nonsense mediated mRNA decay.
    
 0.990
UPF1
UPF1 RNA helicase and ATPase.
    
 0.990
UPF3B
UPF3B regulator of nonsense mediated mRNA decay.
    
 0.986
UPF3A
UPF3A regulator of nonsense mediated mRNA decay.
    
 0.983
MAGOHB
Mago homolog B, exon junction complex subunit.
    
 0.978
MAGOH
Mago homolog, exon junction complex subunit.
    
 0.973
ENSNLEP00000027304
Uncharacterized protein.
    
 0.973
PNN
Pinin, desmosome associated protein.
    
 0.945
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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