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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLAURPlasminogen activator, urokinase receptor. (335 aa)    
Predicted Functional Partners:
PLAU
Plasminogen activator, urokinase.
   
 0.995
VTN
SMB domain-containing protein.
    
 
 0.969
PLAT
Plasminogen activator; Belongs to the peptidase S1 family.
   
 0.949
SERPINE1
Serpin family E member 1; Belongs to the serpin family.
   
 0.915
OR5AN1
Olfactory receptor.
      
 0.786
PLG
Apple domain-containing protein.
    
 0.760
EGFR
Receptor protein-tyrosine kinase.
      
 0.691
SRPX2
Sushi repeat containing protein X-linked 2.
      
 0.679
TEX101
Testis expressed 101.
  
 
 
 0.677
TNP2
Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
   
  
 0.674
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.