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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1502 aa)    
Predicted Functional Partners:
NUSAP1
Uncharacterized protein.
   
  
 0.999
ASPM
Abnormal spindle microtubule assembly.
   
  
 0.995
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 
 0.991
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
  
 0.976
TOP2B
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
  
 
0.953
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
  
 0.940
BUB1B
BUB1 N-terminal domain-containing protein.
   
  
 0.934
CENPF
Centromere protein F.
   
  
 0.931
DLGAP5
DLG associated protein 5.
   
  
 0.931
CCNB1
Cyclin B1; Belongs to the cyclin family.
   
 
 0.929
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.