Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EEPD1Endonuclease/exonuclease/phosphatase family domain containing 1. (569 aa)    
Predicted Functional Partners:
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 0.738
IWS1
Interacts with SUPT6H, CTD assembly factor 1.
   
 0.713
SSRP1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.711
EME2
Essential meiotic structure-specific endonuclease subunit 2.
   
  
 0.578
POLR2D
RNA polymerase II subunit D.
    
 0.560
EXO1
Exonuclease 1.
  
  
 0.557
POLR2G
S1 domain-containing protein.
    
 0.540
NEIL3
Nei like DNA glycosylase 3.
      
 0.539
EXO5
Exonuclease 5.
      
 0.523
RTF1
RTF1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.521
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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