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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAPK3Mitogen-activated protein kinase. (278 aa)    
Predicted Functional Partners:
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
  
0.904
PEA15
Proliferation and apoptosis adaptor protein 15.
    
 0.854
MAPK1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
  
0.827
DUSP6
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
    
 0.809
RPS6KA1
Ribosomal protein S6 kinase.
   
0.804
PTPN7
Protein tyrosine phosphatase non-receptor type 7.
    
 0.802
ELK1
ETS transcription factor ELK1.
    
 0.768
MAP2K2
Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.
  
0.762
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
   
 0.749
ENSNLEP00000042936
Protein kinase domain-containing protein.
   
 0.741
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.