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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCRIBScribble planar cell polarity protein. (1449 aa)    
Predicted Functional Partners:
VANGL2
Uncharacterized protein.
    
 0.977
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.972
GIT1
GIT ArfGAP 1.
   
 0.868
VANGL1
Vang-like protein.
    
 0.816
CTNNB1
Catenin beta 1.
   
 0.770
ADGRL1
Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.711
CDH1
Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.710
LATS1
Large tumor suppressor kinase 1.
   
 
 0.701
FAT1
FAT atypical cadherin 1.
      
 0.699
MCC
Uncharacterized protein.
    
 
 0.695
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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