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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIPA1L2Signal induced proliferation associated 1 like 2. (1722 aa)    
Predicted Functional Partners:
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.939
KCNG3
Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family.
   
  
 0.665
RAB11FIP3
RAB11 family interacting protein 3.
      
 0.660
PRR35
Proline rich 35.
      
 0.660
KBTBD12
Kelch repeat and BTB domain containing 12.
      
 0.660
KLC4
Kinesin light chain 4.
      
 0.625
PKDCC
Protein kinase domain containing, cytoplasmic.
     
 0.615
CCDC36
Coiled-coil domain containing 36.
      
 0.604
TMEM43
Transmembrane protein 43.
      
 0.599
VWC2
Von Willebrand factor C domain containing 2.
      
 0.598
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.