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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP10Poly [ADP-ribose] polymerase. (1036 aa)    
Predicted Functional Partners:
NUP205
Nucleoporin 205.
      
 0.804
MCM5
DNA helicase; Belongs to the MCM family.
      
 0.784
LRPPRC
PPR_long domain-containing protein.
      
 0.781
FDPS
Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
      
 0.779
MYC
Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
    
 
 0.744
GRINA
Uncharacterized protein; Belongs to the BI1 family.
   
  
 0.692
PLEC
Plectin.
 
    
 0.650
LDHA
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
  
 0.633
PARP14
Poly [ADP-ribose] polymerase.
   
 
0.605
MACROD2
Mono-ADP ribosylhydrolase 2.
   
 
 0.605
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.