| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CHD4 | HDAC1 | ENSNLEP00000005330 | ENSNLEP00000003167 | Uncharacterized protein. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.993 |
| CHD4 | HDAC2 | ENSNLEP00000005330 | ENSNLEP00000038371 | Uncharacterized protein. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.997 |
| CHD4 | MTA1 | ENSNLEP00000005330 | ENSNLEP00000026716 | Uncharacterized protein. | Metastasis associated 1. | 0.994 |
| CHD4 | MTA2 | ENSNLEP00000005330 | ENSNLEP00000048435 | Uncharacterized protein. | Metastasis associated 1 family member 2. | 0.995 |
| CHD4 | RCOR1 | ENSNLEP00000005330 | ENSNLEP00000032390 | Uncharacterized protein. | REST corepressor 1. | 0.759 |
| CHD4 | SAP30 | ENSNLEP00000005330 | ENSNLEP00000034342 | Uncharacterized protein. | Sin3A associated protein 30. | 0.564 |
| CHD4 | SIN3A | ENSNLEP00000005330 | ENSNLEP00000043924 | Uncharacterized protein. | SIN3 transcription regulator family member A. | 0.663 |
| CTBP1 | HDAC1 | ENSNLEP00000035151 | ENSNLEP00000003167 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.987 |
| CTBP1 | HDAC2 | ENSNLEP00000035151 | ENSNLEP00000038371 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.995 |
| CTBP1 | RCOR1 | ENSNLEP00000035151 | ENSNLEP00000032390 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | REST corepressor 1. | 0.978 |
| CTBP1 | RUNX1 | ENSNLEP00000035151 | ENSNLEP00000041433 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.948 |
| CTBP1 | SIN3A | ENSNLEP00000035151 | ENSNLEP00000043924 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | SIN3 transcription regulator family member A. | 0.483 |
| HDAC1 | CHD4 | ENSNLEP00000003167 | ENSNLEP00000005330 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Uncharacterized protein. | 0.993 |
| HDAC1 | CTBP1 | ENSNLEP00000003167 | ENSNLEP00000035151 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.987 |
| HDAC1 | HDAC2 | ENSNLEP00000003167 | ENSNLEP00000038371 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.999 |
| HDAC1 | MTA1 | ENSNLEP00000003167 | ENSNLEP00000026716 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Metastasis associated 1. | 0.984 |
| HDAC1 | MTA2 | ENSNLEP00000003167 | ENSNLEP00000048435 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Metastasis associated 1 family member 2. | 0.982 |
| HDAC1 | RB1 | ENSNLEP00000003167 | ENSNLEP00000003997 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | RB transcriptional corepressor 1. | 0.997 |
| HDAC1 | RCOR1 | ENSNLEP00000003167 | ENSNLEP00000032390 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | REST corepressor 1. | 0.992 |
| HDAC1 | RUNX1 | ENSNLEP00000003167 | ENSNLEP00000041433 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.989 |
STRING v12.5 is now available!
