| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APBB1 | APLP2 | ENSNLEP00000021127 | ENSNLEP00000035161 | Uncharacterized protein. | Amyloid beta precursor like protein 2. | 0.917 |
| APBB1 | APP | ENSNLEP00000021127 | ENSNLEP00000026435 | Uncharacterized protein. | Amyloid beta precursor protein. | 0.972 |
| APBB1 | BACE1 | ENSNLEP00000021127 | ENSNLEP00000041003 | Uncharacterized protein. | Beta-secretase 1; Belongs to the peptidase A1 family. | 0.500 |
| APBB1 | NAE1 | ENSNLEP00000021127 | ENSNLEP00000004923 | Uncharacterized protein. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.528 |
| APLP2 | APBB1 | ENSNLEP00000035161 | ENSNLEP00000021127 | Amyloid beta precursor like protein 2. | Uncharacterized protein. | 0.917 |
| APLP2 | APOE | ENSNLEP00000035161 | ENSNLEP00000002097 | Amyloid beta precursor like protein 2. | Apolipoprotein E. | 0.794 |
| APLP2 | APP | ENSNLEP00000035161 | ENSNLEP00000026435 | Amyloid beta precursor like protein 2. | Amyloid beta precursor protein. | 0.969 |
| APLP2 | BACE1 | ENSNLEP00000035161 | ENSNLEP00000041003 | Amyloid beta precursor like protein 2. | Beta-secretase 1; Belongs to the peptidase A1 family. | 0.760 |
| APLP2 | CLU | ENSNLEP00000035161 | ENSNLEP00000020006 | Amyloid beta precursor like protein 2. | Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. | 0.758 |
| APLP2 | MAPT | ENSNLEP00000035161 | ENSNLEP00000005820 | Amyloid beta precursor like protein 2. | Microtubule-associated protein. | 0.628 |
| APLP2 | NAE1 | ENSNLEP00000035161 | ENSNLEP00000004923 | Amyloid beta precursor like protein 2. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.592 |
| APLP2 | PSEN1 | ENSNLEP00000035161 | ENSNLEP00000031012 | Amyloid beta precursor like protein 2. | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. | 0.687 |
| APLP2 | SNCA | ENSNLEP00000035161 | ENSNLEP00000017444 | Amyloid beta precursor like protein 2. | Alpha-synuclein; Belongs to the synuclein family. | 0.768 |
| APLP2 | SORL1 | ENSNLEP00000035161 | ENSNLEP00000028705 | Amyloid beta precursor like protein 2. | Sortilin related receptor 1. | 0.876 |
| APOE | APLP2 | ENSNLEP00000002097 | ENSNLEP00000035161 | Apolipoprotein E. | Amyloid beta precursor like protein 2. | 0.794 |
| APOE | APP | ENSNLEP00000002097 | ENSNLEP00000026435 | Apolipoprotein E. | Amyloid beta precursor protein. | 0.980 |
| APOE | BACE1 | ENSNLEP00000002097 | ENSNLEP00000041003 | Apolipoprotein E. | Beta-secretase 1; Belongs to the peptidase A1 family. | 0.503 |
| APOE | CLU | ENSNLEP00000002097 | ENSNLEP00000020006 | Apolipoprotein E. | Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. | 0.834 |
| APOE | MAPT | ENSNLEP00000002097 | ENSNLEP00000005820 | Apolipoprotein E. | Microtubule-associated protein. | 0.937 |
| APOE | PSEN1 | ENSNLEP00000002097 | ENSNLEP00000031012 | Apolipoprotein E. | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. | 0.695 |
