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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KNL1Kinetochore scaffold 1. (2331 aa)    
Predicted Functional Partners:
NAP1L4
Nucleosome assembly protein 1 like 4; Belongs to the nucleosome assembly protein (NAP) family.
    
 
 0.600
HIRIP3
HIRA interacting protein 3.
      
 0.564
CENPE
Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.537
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.536
DSN1
DSN1 component of MIS12 kinetochore complex.
   
 0.534
NSL1
NSL1 component of MIS12 kinetochore complex.
   
 0.533
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 0.532
BUB1B
BUB1 N-terminal domain-containing protein.
   
 
 0.514
CENPI
Centromere protein I.
   
 0.513
NDC80
NDC80 kinetochore complex component.
   
 0.512
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.