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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1120 aa)    
Predicted Functional Partners:
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 0.998
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
   
 0.996
ENSNLEP00000038312
Uncharacterized protein; Belongs to the heat shock protein 70 family.
   
 0.988
ATF4
BZIP domain-containing protein.
     
 0.964
NFE2L2
Nuclear factor, erythroid 2 like 2.
   
 0.953
EIF2AK4
Eukaryotic translation initiation factor 2 alpha kinase 4.
   
 
0.951
EIF2AK1
Eukaryotic translation initiation factor 2 alpha kinase 1.
   
 
0.943
PSEN1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
     
 0.927
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
0.915
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
0.915
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.