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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLE1TLE family member 1, transcriptional corepressor. (765 aa)    
Predicted Functional Partners:
TLE4
TLE family member 4, transcriptional corepressor.
  
 
0.928
TLE3
TLE family member 3, transcriptional corepressor.
  
 
0.898
LEF1
Lymphoid enhancer binding factor 1.
    
 0.881
RASEF
RAS and EF-hand domain containing.
    
 
 0.863
FRMD3
FERM domain containing 3.
      
 0.863
TLE5
TLE_N domain-containing protein.
    
0.833
SNRPN
Small nuclear ribonucleoprotein-associated protein.
      
 0.779
ENSNLEP00000044923
Uncharacterized protein.
  
 
0.769
RIPPLY1
Ripply transcriptional repressor 1.
    
 
 0.764
VENTX
Homeobox domain-containing protein.
    
 
 0.755
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.