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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRHL2Grainyhead like transcription factor 2. (625 aa)    
Predicted Functional Partners:
ESRP1
Epithelial splicing regulatory protein 1.
   
  
 0.845
ENSNLEP00000045603
Uncharacterized protein.
   
  
 0.617
KMT2C
Lysine methyltransferase 2C.
   
 
 0.525
OVOL1
Ovo like transcriptional repressor 1.
   
  
 0.490
GATA3
GATA binding protein 3.
   
  
 0.456
HOXB13
Homeobox B13.
    
 
 0.455
ZEB1
Zinc finger E-box binding homeobox 1.
      
 0.451
RAB25
RAB25, member RAS oncogene family.
   
 
 0.435
LMO4
LIM domain only 4.
    
 
 0.424
FOXA1
Uncharacterized protein.
   
 
 0.421
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.