Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
STYK1Serine/threonine/tyrosine kinase 1. (422 aa)    
Predicted Functional Partners:
ERBB2
Receptor protein-tyrosine kinase.
    
 0.688
NSMCE1
NSE1 homolog, SMC5-SMC6 complex component.
      
 0.678
RASAL2
RAS protein activator like 2.
   
 0.617
SSBP2
Single stranded DNA binding protein 2.
      
 0.500
MPP6
Membrane palmitoylated protein 6; Belongs to the MAGUK family.
    
 
 0.497
KITLG
Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.
    
 0.495
SGK3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
 0.487
RBMS3
RNA binding motif single stranded interacting protein 3.
      
 0.466
RSF1
Remodeling and spacing factor 1.
     
 0.466
UBE4B
Ubiquitination factor E4B.
    
 
 0.459
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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