VWF protein (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

VWF

Von Willebrand factor. (2790 aa)

Predicted Functional Partners:

F8

0.999

GP1BA

0.997

ITGA2B

0.995

GP1BB

0.987

ITGB3

0.983

F10

0.964

SELP

0.953

ADAMTS13

0.935

GP6

0.905

F2

0.861

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAMTS13	F2	ENSNLEP00000015993	ENSNLEP00000017190	ADAM metallopeptidase with thrombospondin type 1 motif 13.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.502
ADAMTS13	F8	ENSNLEP00000015993	ENSNLEP00000017554	ADAM metallopeptidase with thrombospondin type 1 motif 13.	Coagulation factor VIII; Belongs to the multicopper oxidase family.	0.741
ADAMTS13	GP1BA	ENSNLEP00000015993	ENSNLEP00000021145	ADAM metallopeptidase with thrombospondin type 1 motif 13.	Glycoprotein Ib platelet subunit alpha.	0.714
ADAMTS13	SELP	ENSNLEP00000015993	ENSNLEP00000018249	ADAM metallopeptidase with thrombospondin type 1 motif 13.	Selectin P.	0.480
ADAMTS13	VWF	ENSNLEP00000015993	ENSNLEP00000004210	ADAM metallopeptidase with thrombospondin type 1 motif 13.	Von Willebrand factor.	0.935
F10	F2	ENSNLEP00000000601	ENSNLEP00000017190	Coagulation factor X.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.992
F10	F8	ENSNLEP00000000601	ENSNLEP00000017554	Coagulation factor X.	Coagulation factor VIII; Belongs to the multicopper oxidase family.	0.944
F10	GP1BA	ENSNLEP00000000601	ENSNLEP00000021145	Coagulation factor X.	Glycoprotein Ib platelet subunit alpha.	0.451
F10	SELP	ENSNLEP00000000601	ENSNLEP00000018249	Coagulation factor X.	Selectin P.	0.430
F10	VWF	ENSNLEP00000000601	ENSNLEP00000004210	Coagulation factor X.	Von Willebrand factor.	0.964
F2	ADAMTS13	ENSNLEP00000017190	ENSNLEP00000015993	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	ADAM metallopeptidase with thrombospondin type 1 motif 13.	0.502
F2	F10	ENSNLEP00000017190	ENSNLEP00000000601	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor X.	0.992
F2	F8	ENSNLEP00000017190	ENSNLEP00000017554	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor VIII; Belongs to the multicopper oxidase family.	0.936
F2	GP1BA	ENSNLEP00000017190	ENSNLEP00000021145	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Glycoprotein Ib platelet subunit alpha.	0.964
F2	GP1BB	ENSNLEP00000017190	ENSNLEP00000026615	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Glycoprotein Ib platelet subunit beta.	0.626
F2	GP6	ENSNLEP00000017190	ENSNLEP00000012962	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Ig-like domain-containing protein.	0.439
F2	ITGA2B	ENSNLEP00000017190	ENSNLEP00000000204	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.	0.447
F2	SELP	ENSNLEP00000017190	ENSNLEP00000018249	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Selectin P.	0.496
F2	VWF	ENSNLEP00000017190	ENSNLEP00000004210	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Von Willebrand factor.	0.861
F8	ADAMTS13	ENSNLEP00000017554	ENSNLEP00000015993	Coagulation factor VIII; Belongs to the multicopper oxidase family.	ADAM metallopeptidase with thrombospondin type 1 motif 13.	0.741

page 1 of 5

Server load: low (40%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About