Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2778 aa)    
Predicted Functional Partners:
BUB3
BUB3 mitotic checkpoint protein.
    
 
 0.926
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
    
   0.921
TRIP12
Thyroid hormone receptor interactor 12.
   
  
 0.886
BUB1B
BUB1 N-terminal domain-containing protein.
    
   0.841
MYC
Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
   
 
 0.833
ENSNLEP00000027897
Uncharacterized protein.
    
 
 0.786
ZUP1
Zinc finger containing ubiquitin peptidase 1.
    
 
 0.784
DYRK2
Dual specificity tyrosine phosphorylation regulated kinase 2.
   
 
 0.784
CEP78
Centrosomal protein 78.
    
 
 0.780
MCRS1
Microspherule protein 1.
    
   0.778
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.