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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2778 aa)    
Predicted Functional Partners:
TRIP12
Thyroid hormone receptor interactor 12.
   
  
0.960
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
    
   0.806
ARFGEF1
ADP ribosylation factor guanine nucleotide exchange factor 1.
   
    0.768
BUB3
BUB3 mitotic checkpoint protein.
    
 
 0.765
PAIP1
Poly(A) binding protein interacting protein 1.
   
 
 0.749
UBR1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
  
 0.723
DYRK2
Dual specificity tyrosine phosphorylation regulated kinase 2.
   
 
 0.721
BUB1B
BUB1 N-terminal domain-containing protein.
    
   0.719
ZUP1
Zinc finger containing ubiquitin peptidase 1.
    
 
 0.694
USP34
Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family.
   
  
 0.692
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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