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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCH1Phosphoinositide phospholipase C. (1693 aa)    
Predicted Functional Partners:
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
   
 0.923
IPMK
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.912
INPP5K
Inositol polyphosphate-5-phosphatase K.
     
 0.907
INPP5J
Inositol polyphosphate-5-phosphatase J.
     
 0.907
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.903
SYNJ2
Synaptojanin 2.
   
  0.903
OCRL
OCRL inositol polyphosphate-5-phosphatase.
     
 0.902
MINPP1
Multiple inositol-polyphosphate phosphatase 1; Belongs to the histidine acid phosphatase family.
     
  0.900
PIP5K1B
Phosphatidylinositol-4-phosphate 5-kinase type 1 beta.
   
 0.733
PIP5K1A
Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha.
   
 0.732
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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