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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (687 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.991
CTNND1
Catenin delta 1.
    
 0.988
PECAM1
Platelet and endothelial cell adhesion molecule 1.
   
 0.976
KDR
Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 
 0.970
TJP1
Tight junction protein 1; Belongs to the MAGUK family.
   
 0.868
PTPRB
Protein tyrosine phosphatase receptor type B.
   
 0.865
JUP
Junction plakoglobin.
    
 0.855
CDH1
Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.
     
0.854
CTNNA1
Catenin alpha 1.
    
 0.851
ENSNLEP00000040381
Uncharacterized protein.
    
 0.851
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.