Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NPR2Guanylate cyclase. (1038 aa)    
Predicted Functional Partners:
NPPC
Natriuretic peptide C.
    
 0.996
NPPB
Natriuretic peptide B.
    
 0.926
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase 3.
     
 0.906
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
     
 0.906
NPR1
Guanylate cyclase.
  
  
0.904
NUDT2
Nudix hydrolase 2.
     
  0.900
PDE3A
Phosphodiesterase.
   
 0.895
PDE5A
Phosphodiesterase.
   
 0.812
MOCS1
Molybdenum cofactor synthesis 1.
   
 
 0.807
GCH1
GTP cyclohydrolase 1.
     
 0.807
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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