| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGO1 | AGO2 | ENSNLEP00000013638 | ENSNLEP00000001761 | Argonaute RISC component 1; Belongs to the argonaute family. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.997 |
| AGO1 | DICER1 | ENSNLEP00000013638 | ENSNLEP00000021032 | Argonaute RISC component 1; Belongs to the argonaute family. | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.997 |
| AGO1 | FMR1 | ENSNLEP00000013638 | ENSNLEP00000016151 | Argonaute RISC component 1; Belongs to the argonaute family. | Fragile X mental retardation 1. | 0.837 |
| AGO1 | MOV10 | ENSNLEP00000013638 | ENSNLEP00000005118 | Argonaute RISC component 1; Belongs to the argonaute family. | Mov10 RISC complex RNA helicase. | 0.838 |
| AGO1 | PUM2 | ENSNLEP00000013638 | ENSNLEP00000033824 | Argonaute RISC component 1; Belongs to the argonaute family. | Pumilio RNA binding family member 2. | 0.539 |
| AGO1 | TNRC6B | ENSNLEP00000013638 | ENSNLEP00000034946 | Argonaute RISC component 1; Belongs to the argonaute family. | Trinucleotide repeat containing adaptor 6B. | 0.966 |
| AGO1 | UPF1 | ENSNLEP00000013638 | ENSNLEP00000041591 | Argonaute RISC component 1; Belongs to the argonaute family. | UPF1 RNA helicase and ATPase. | 0.612 |
| AGO2 | AGO1 | ENSNLEP00000001761 | ENSNLEP00000013638 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Argonaute RISC component 1; Belongs to the argonaute family. | 0.997 |
| AGO2 | DICER1 | ENSNLEP00000001761 | ENSNLEP00000021032 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.998 |
| AGO2 | EIF6 | ENSNLEP00000001761 | ENSNLEP00000012447 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | 0.602 |
| AGO2 | FMR1 | ENSNLEP00000001761 | ENSNLEP00000016151 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Fragile X mental retardation 1. | 0.877 |
| AGO2 | MOV10 | ENSNLEP00000001761 | ENSNLEP00000005118 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Mov10 RISC complex RNA helicase. | 0.911 |
| AGO2 | PUM2 | ENSNLEP00000001761 | ENSNLEP00000033824 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Pumilio RNA binding family member 2. | 0.687 |
| AGO2 | TNRC6B | ENSNLEP00000001761 | ENSNLEP00000034946 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Trinucleotide repeat containing adaptor 6B. | 0.978 |
| AGO2 | UPF1 | ENSNLEP00000001761 | ENSNLEP00000041591 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | UPF1 RNA helicase and ATPase. | 0.737 |
| CBX6 | MOV10 | ENSNLEP00000018459 | ENSNLEP00000005118 | Chromobox 6. | Mov10 RISC complex RNA helicase. | 0.646 |
| DICER1 | AGO1 | ENSNLEP00000021032 | ENSNLEP00000013638 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | Argonaute RISC component 1; Belongs to the argonaute family. | 0.997 |
| DICER1 | AGO2 | ENSNLEP00000021032 | ENSNLEP00000001761 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.998 |
| DICER1 | EIF6 | ENSNLEP00000021032 | ENSNLEP00000012447 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | 0.439 |
| DICER1 | FMR1 | ENSNLEP00000021032 | ENSNLEP00000016151 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | Fragile X mental retardation 1. | 0.822 |
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