NLRP3 protein (Nomascus leucogenys) - STRING interaction network

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Predicted Interactions

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Score

NLRP3

NLR family pyrin domain containing 3. (1020 aa)

Predicted Functional Partners:

TXNIP

0.973

PYCARD

0.973

NEK7

0.965

IL1B

0.947

CASP1

0.946

HSP90AA1

0.920

RELA

0.917

CARD8

0.911

NFKB1

0.908

MAVS

0.598

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CARD8	IL1B	ENSNLEP00000044515	ENSNLEP00000044905	FIIND domain-containing protein.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.429
CARD8	NLRP3	ENSNLEP00000044515	ENSNLEP00000005171	FIIND domain-containing protein.	NLR family pyrin domain containing 3.	0.911
CARD8	PYCARD	ENSNLEP00000044515	ENSNLEP00000019741	FIIND domain-containing protein.	PYD and CARD domain containing.	0.454
CASP1	IL1B	ENSNLEP00000044525	ENSNLEP00000044905	Caspase 1; Belongs to the peptidase C14A family.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.998
CASP1	MAVS	ENSNLEP00000044525	ENSNLEP00000009315	Caspase 1; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.470
CASP1	NEK7	ENSNLEP00000044525	ENSNLEP00000021946	Caspase 1; Belongs to the peptidase C14A family.	NIMA related kinase 7; Belongs to the protein kinase superfamily.	0.721
CASP1	NFKB1	ENSNLEP00000044525	ENSNLEP00000016247	Caspase 1; Belongs to the peptidase C14A family.	Nuclear factor kappa B subunit 1.	0.663
CASP1	NLRP3	ENSNLEP00000044525	ENSNLEP00000005171	Caspase 1; Belongs to the peptidase C14A family.	NLR family pyrin domain containing 3.	0.946
CASP1	PYCARD	ENSNLEP00000044525	ENSNLEP00000019741	Caspase 1; Belongs to the peptidase C14A family.	PYD and CARD domain containing.	0.999
CASP1	TXNIP	ENSNLEP00000044525	ENSNLEP00000007046	Caspase 1; Belongs to the peptidase C14A family.	Thioredoxin interacting protein.	0.658
HSP90AA1	IL1B	ENSNLEP00000025829	ENSNLEP00000044905	Heat shock protein 90 alpha family class A member 1.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.574
HSP90AA1	MAVS	ENSNLEP00000025829	ENSNLEP00000009315	Heat shock protein 90 alpha family class A member 1.	Uncharacterized protein.	0.572
HSP90AA1	NFKB1	ENSNLEP00000025829	ENSNLEP00000016247	Heat shock protein 90 alpha family class A member 1.	Nuclear factor kappa B subunit 1.	0.528
HSP90AA1	NLRP3	ENSNLEP00000025829	ENSNLEP00000005171	Heat shock protein 90 alpha family class A member 1.	NLR family pyrin domain containing 3.	0.920
HSP90AA1	TXNIP	ENSNLEP00000025829	ENSNLEP00000007046	Heat shock protein 90 alpha family class A member 1.	Thioredoxin interacting protein.	0.514
IL1B	CARD8	ENSNLEP00000044905	ENSNLEP00000044515	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	FIIND domain-containing protein.	0.429
IL1B	CASP1	ENSNLEP00000044905	ENSNLEP00000044525	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Caspase 1; Belongs to the peptidase C14A family.	0.998
IL1B	HSP90AA1	ENSNLEP00000044905	ENSNLEP00000025829	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Heat shock protein 90 alpha family class A member 1.	0.574
IL1B	MAVS	ENSNLEP00000044905	ENSNLEP00000009315	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Uncharacterized protein.	0.458
IL1B	NEK7	ENSNLEP00000044905	ENSNLEP00000021946	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	NIMA related kinase 7; Belongs to the protein kinase superfamily.	0.493

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