STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIMK2LIM domain kinase 2. (638 aa)    
Predicted Functional Partners:
CFL1
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 0.988
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 0.980
PAK1
Non-specific serine/threonine protein kinase.
    
0.954
PAK2
Non-specific serine/threonine protein kinase.
    
0.953
PAK4
Non-specific serine/threonine protein kinase.
    
0.953
ROCK1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
   
0.952
ROCK2
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
   
0.950
PAK6
Non-specific serine/threonine protein kinase.
    
0.942
PAK5
Non-specific serine/threonine protein kinase.
    
0.942
ENSNLEP00000041102
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 0.890
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.